“Fatigue” having a role in the pathogenesis of osteonecrosis of the jaws
✍ Scribed by Athanassios Kyrgidis; Konstantinos Vahtsevanos
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 54 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1432-6981
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## Abstract Two unusual cases of osteonecrosis of the jaws in edentulous patients are described. One case involved the maxilla and the other the mandible. Both patients were compromised hosts who were undergoing cancer chemotherapy. Both developed local mucosal infections beneath their dentures bef
## Abstract Osteonecrosis of the jaws (ONJ) associated with the use of bisphosphonates is a newly described entity. To elucidate the mechanism leading to ONJ and to test the hypothesis that in patients with ONJ the bisphosphonates may interfere with endothelial cell proliferation, using flow cytome