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Fate of hexachlorobenzene in C57BL/10 mice with iron overload

โœ Scribed by Ravindra N. Khanna; Andrew G. Smith


Book ID
115778148
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
637 KB
Volume
34
Category
Article
ISSN
0006-2952

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Pre-loading of C57BUIOScSn mice with iron greatly sensitizes them to the induction of hepatic porphyria caused by hexachlorobenzene (HCB) (Smith and Francis, 1983). HCB will also cause liver tumours in experimental animals. Elevated liver iron stores are implicated in the development of some human l