Fatal varicella-zoster virus meningoradiculitis without skin involvement

✍ Scribed by Dr Aud N. Dueland; Mary Devlin; John R. Martin; Ravi Mahalingam; Randall Cohrs; Herbert Manz; Irene Trombley; Donald Gilden

• Book ID: 101468691
• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 471 KB
• Volume: 29
• Category: Article
• ISSN: 0364-5134
• DOI: 10.1002/ana.410290520

✦ Synopsis

The phenotypic variability of mitochondrial disorders is remarkable and has been explained by the peculiarities of mitochondrial inheritance, although acquired factors may also have a role C9, 14). Mitochondrial dysfunction provides an attractive unifying explanation for the diverse clinical and laboratory features of MSL. The frequent association of MSL with alcoholism provides the clearest example, to date, of the interaction between acquired and genetic factors in this new and expanding family of metabolic diseases.