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Fatal reye-like syndrome associated with valproic acid

✍ Scribed by Richard S. K. Young; Ira Bergman; David L. Gang; Edward P. Richardson Jr


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
109 KB
Volume
7
Category
Article
ISSN
0364-5134

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## Abstract A 56‐year‐old woman with an acute promyelocytic leukemia (APL) developed a severe __all‐trans__‐retinoic (ATRA) syndrome on day 17 of treatment. Shortly after, she presented a picture of pancytopenia, hepatosplenomegaly, increased triglycerides, ferritin, and liver enzymes. A bone marro