✦ LIBER ✦

Fatal invasive aspergillosis in an adolescent with cystic fibrosis

✍ Scribed by K. Brown; M. Rosenthal; Andrew Bush

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 147 KB
Volume: 27
Category: Article
ISSN: 8755-6863
DOI: 10.1002/(sici)1099-0496(199902)27:2<130::aid-ppul10>3.0.co;2-1

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✦ Synopsis

We report on a 13-year-old girl with cystic fibrosis (CF) who developed refractory airflow obstruction despite high-dose steroids. She developed invasive aspergillosis and died despite oral and intravenous antifungal therapy. We speculate that the increasing use of immunosuppressive strategies and aggressive antipseudomonal therapy in CF may lead to an increase in aspergillus lung disease, including invasive aspergillosis in the future.

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