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Fatal illness associated with a new hantavirus in Louisiana

✍ Scribed by Ali S. Khan; Christina F. Spiropoulou; Sergey Morzunov; Sherif R. Zaki; Melvin A. Kohn; Soheir R. Nawas; Louise McFarland; Dr. Stuart T. Nichol

Book ID
102909759
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
544 KB
Volume
46
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

A fatal case of hantaviral illness occurred in Louisiana, outside of the range of P. maniculatus, the rodent reservoir for Sin Nombre virus. Hantavirus RNA and antigens were detected in patient autopsy tissues, and nucleotide sequence analysis of amplified polymerase chain reaction (PCR) products identified a newly recognized unique hantavirus, provisionally named Bayou virus. Prominent features of the clinical illness are compatible with hantavirus pulmonary syndrome (HPS), but several features such as renal insufficiency and intraalveolar hemorrhage are more compatible with hemorrhagic fever with renal syndrome (HFRS), a disease associated with Eurasian hantaviruses. Β© 1995 Wiley‐Liss, Inc.

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