Abnormal metabolism of valproic acid in
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W. Kochen; A. Schneider; A. Ritz
📂
Article
📅
1983
🏛
Springer
🌐
English
⚖ 633 KB
A 7-year-old boy developed a severe unilateral grand real seizure at the age of 5 years (phenobarbitone therapy); 1.5 years later valproate (2-propylpentanoic acid, VPA) was added to the therapy. After a seizure-free period of 3 months the patient died from hepatic failure resembling Reye syndrome.