Fatal giant cell myocarditis after thymoma resection in myasthenia gravis

Normalization of elevated CD4−/CD8− (dou

Normalization of elevated CD4−/CD8− (double-negative) T cells after thymectomy parallels clinical remission in myasthenia gravis associated with thymic hyperplasia but not thymoma

✍ Carsten Reinhardt; Arthur Melms 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB 👁 2 views

T-cell-dependent B-cell help is likely to be of major importance in the pathogenesis of myasthenia gravis, but mechanisms provoking a pathological anti-acetylcholine receptor (AChR) response are poorly understood. We report on the dysregulation of recently identified CD4 ؊ /CD8 ؊ (double-negative) T