Fatal aplastic anemia associated with allopurinol therapy
β Scribed by M. E. Conrad
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 111 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0361-8609
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π SIMILAR VOLUMES
Five consecutive patients with severe aplastic anemia were treated with antithymocyte globulin followed by cyclosporin A. All received antithymocyte globulin initially, and because of lack of response within a 4 week period, cyclosporin was administered subsequently. Hematologic improvement occurred
Several investigators have reported patients with acute pure red cell aplasia (PRCA) caused by anticonvulsants, antibiotics, or antithyroid agents. Allopurinol is known to be a causative agent of aplastic anemia, but there have been few reports of acute PRCA induced by allopurinol. We describe here