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Fast, transient DNA damage by benzo[a]pyrene

✍ Scribed by Rudolf K. Zahn; Johanna Höhn-Bentz; Branko Kurelec


Book ID
119067750
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
61 KB
Volume
14
Category
Article
ISSN
0141-1136

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## Abstract Benzo[__a__]pyrene (B[__a__]P) is an environmental carcinogenic polycyclic aromatic hydrocarbon (PAH). Mammalian enzymes such as cytochrome P‐450s and epoxide hydrase convert B[__a__]P to reactive metabolites that can covalently bind to DNA. However, some carcinogenic compounds that nor