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Fast Three-Dimensional Imaging and Tracking of Single Molecules in the Nucleus of Live Cells using a Multifocal Microscope

✍ Scribed by Chen, Jiji; Hajj, Bassam; Abrahamsson, Sara; Grunwald, David; Gustaffson, Mats; Dahan, Maxime


Book ID
122263485
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
35 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract Gold nanoparticles (AuNPs) confined in liposomes of diameters around 200 nm produce strong scattering signal owing to surface plasmon resonance, and therefore bright‐field optical tracking of the AuNP‐encapsulating liposomes can be conducted in living cells. Using an optical profiling t