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Fast spin-echo characteristics of visual stimulation-induced signal changes in the human brain

✍ Scribed by Jia-Hong Gao; Jinhu Xiong; Jinqi Li; Joseph Schiff; John Roby; Jack L. Lancaster; Peter T. Fox

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
725 KB
Volume
5
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

A fast spin‐echo (FSE) technique used in a conventional MR imaging scanner has been successfully developed for obtaining functional MR images with high spatial resolution and multiple slices. Our preliminary visual stimulation studies using the FSE technique show that the nuclear MR signal increases by 2.6% during activation in the primary visual cortex. These results provide evidence that the diffusion of tissue water molecules plays a key role in determining functional MR signal amplitude. Because the FSE functional MR imaging signal is extremely sensitive to microvascular (brain capillaries) hemodynamics, the FSE technique can be a powerful tool for studying the neuronal activity of the human brain.

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