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Fast comparison of DNA sequences by oligonucleotide profiling

✍ Scribed by Vicente Arnau; Miguel Gallach; Ignacio Marín


Book ID
115024530
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
229 KB
Volume
1
Category
Article
ISSN
1756-0500

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## Abstract ## Background Single‐stranded oligonucleotides (ssODN) can induce site‐specific genetic alterations in selected mammalian cells, but the involved mechanisms are not known. ## Methods We corroborate the potential of genomic sequence correction by ssODN using chromosomally integrated m