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Fast Adaptation in Vestibular Hair Cells Requires Myosin-1c Activity

✍ Scribed by Eric A. Stauffer; John D. Scarborough; Moritoshi Hirono; Emilie D. Miller; Kavita Shah; John A. Mercer; Jeffrey R. Holt; Peter G. Gillespie


Book ID
116782414
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
733 KB
Volume
47
Category
Article
ISSN
0896-6273

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## Abstract **Background:** Cell lines that stably over‐express protein kinase C (PKC) Ξ΄ frequently show a decrease in growth rate and saturation density, leading to the hypothesis that PKCΞ΄ has a negative effect on cell proliferation. However, the mode of PKCΞ΄ activation, the cell cycle stage requ