## Magnetic resonance chemical shift imaging (CSI) is becoming To cope with the long experimental duration, a number the method of choice for localized NMR spectroscopic examinaof fast CSI sequences have been developed in the past years, tions, allowing simultaneous detection of NMR spectra from a
Fast 31P chemical shift imaging using SSFP methods
โ Scribed by O. Speck; K. Scheffler; J. Hennig
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 484 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0740-3194
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โฆ Synopsis
Abstract
Steadyโstate free precession (SSFP) methods have been very successful due to their high signal and short imaging times. These properties make them good candidates for applications that intrinsically suffer from low signal such as low gamma nuclei imaging. A new chemical shift imaging (CSI) technique based on the SSFP signal formation has been implemented and applied to ^31^P. The signal properties of the SSFP CSI method have been evaluated and the steadyโstate signal of ^31^P has been measured in human muscles. Due to the T~2~ and T~1~ signal dependence of SSFP, the steadyโstate signal mainly consists of phosphocreatine (PCr). The technique allows fast CSI acquisitions with high SNR of the PCr signal. The SNR gain for PCr over a FLASHโbased CSI method is approx. 4โ5. Fast in vivo CSI of human muscle with subcentimeter resolution and high SNR is demonstrated at 2 T. Magn Reson Med 48:633โ639, 2002. ยฉ 2002 WileyโLiss, Inc.
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