✦ LIBER ✦
Fast 13C-glucose metabolite mapping in rat brain using 1H echo planar spectroscopic imaging technique at 2T
✍ Scribed by Shigehiro Morikawa; Toshiro Inubushi
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 146 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
For fast ^13^C metabolite mapping in rat brains, ^1^H‐detected ^13^C NMR spectroscopy using gradient‐enhanced heteronuclear multiple‐quantum coherence and ^1^H echo planar spectroscopic imaging were combined. ^13^C glucose and 3‐/4‐^13^C‐Glu/Gln images of rat brain were successfully constructed with 35‐minute temporal resolution under a 2T magnetic field. In the ischemic region of the suture middle cerebral artery occlusion model, glucose and Glu/Gln signals decreased and lactate signals appeared. J. Magn. Reson. Imaging 2001;13:787–791. © 2001 Wiley‐Liss, Inc.