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FASCINATE: A pulse sequence for simultaneous acquisition of T2-weighted and fluid-attenuated images

✍ Scribed by Kazuhiro Takeo; Akihiro Ishikawa; Masato Okazaki; Satoru Kohno; Koji Shimizu


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
227 KB
Volume
51
Category
Article
ISSN
0740-3194

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✦ Synopsis


Abstract

A pulse sequence that enables simultaneous acquisition of T~2~‐weighted and fluid‐attenuated images is presented. This sequence is referred to as FASCINATE (Fluid‐Attenuated Scan Combined with Interleaved Non‐ATtEnuation). In this new technique, the inversion pulse of conventional fast fluid‐attenuated inversion recovery (FLAIR) is replaced with a fast spin echo (FSE) acquisition that has an additional 180(y)–90(x) pulse train for driven inversion. By using appropriate scan parameters, the first part of the sequence provides T~2~‐weighted images and the second part provides fluid‐attenuated images, thus allowing simultaneous acquisition in a single scan time comparable to that of fast FLAIR. FASCINATE was compared with conventional scanning techniques using a normal volunteer and a patient. A signal simulation was also conducted. In the human study, both T~2~‐weighted and fluid‐attenuated images from FASCINATE showed the same image quality as conventional images, suggesting the potential for this technique to replace the combination of fast FLAIR and T~2~‐weighted FSE for scan time reduction. Magn Reson Med 51:205–211, 2004. © 2003 Wiley‐Liss, Inc.


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