Lack of UCP2 reduces fas-mediated liver
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Péter Fülöp; Zoltán Derdák; Anthony Sheets; Edmond Sabo; Eric P. Berthiaume; Mur
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Article
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2006
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John Wiley and Sons
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English
⚖ 901 KB
Fatty liver is vulnerable to conditions that challenge hepatocellular energy homeostasis. Lipidladen hepatocytes highly express uncoupling protein-2 (UCP2), a mitochondrial carrier that competes with adenosine triphosphate (ATP) synthesis by mediating proton leak. However, evidence for a link betwee