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Fas-Mediated Induction of Hepatocyte Apoptosis in a Neuroblastoma and Hepatocyte Coculture Model

✍ Scribed by Mike K. Chen; Louise F. Strande; Elizabeth A. Beierle; Michael S. Kain; Brian D. Geldziler; Edward J. Doolin

Book ID
115635878
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
70 KB
Volume
84
Category
Article
ISSN
0022-4804

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## Abstract Incubation of primary cultures of parenchymal hepatocytes in a conditioned medium (CM), collected over the first 3 h of serum‐free rat hepatocyte culture (CM~0–3~), induces a time dependent increase of the frequency of apoptotic cells which is accompanied by prominent changes of cell mo