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Fas ligand expressed in colon cancer is associated with suppression of activation and IL-2 production in tumor-infiltrating T-cells

✍ Scribed by Houston, Aileen; Bennett, Michael W.; O'Sullivan, Gerald C.; Shanahan, Fergus; O'Connell, Joe


Book ID
124105484
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
191 KB
Volume
120
Category
Article
ISSN
0016-5085

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Fas ligand expressed in colon cancer is
✍ Aileen Houston; Frank D. Waldron-Lynch; Michael W. Bennett; Desmond Roche; Geral πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 267 KB

## Abstract Expression of Fas ligand (FasL/CD95L) may help to maintain colon cancers in a state of immune privilege by inducing apoptosis of antitumor immune effector cells. Colon tumor‐derived cell lines appear to be relatively insensitive to apoptosis mediated by their own or exogenous FasL __in