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Fas ligand and immune evasion

✍ Scribed by Nagata, Shigekazu

Book ID
109932687
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
319 KB
Volume
2
Category
Article
ISSN
1078-8956

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Fas ligand (FasL) kills sensitive Fas receptor (FasR)-bearing cells by inducing apoptosis. FasL expressed by non-lymphoid cells within the eye and the testis mediates immune privilege by inducing apoptosis of Fas-sensitive infiltrating pro-inflammatory immune effector cells. It has previously been d