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Fas-induced apoptosis of human B cells can be inhibited by over-expression of Bcl-2

✍ Scribed by M.K. Alam; S. Davison; J.D. Norton; J.J. Murphy

Book ID
108408720
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
188 KB
Volume
56
Category
Article
ISSN
0165-2478

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In this study we evaluated the effect of over-expression of the bcl-2 gene, a potent apoptosis suppressor, on radiationinduced apoptotic cell death in 2 human prostate cancer cell lines, androgen-independent PC-3 cells and androgen-sensitive LNCaP cells. Cells were transfected with the bcl-2 gene an