The resolution of lesions induced by Lei
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Fatima Conceição-Silva; Michael Hahne; Michael Schröter; Jacques Louis; Jürg Tsc
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Article
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1998
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John Wiley and Sons
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English
⚖ 153 KB
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Normal or perforin-deficient C57BL/6 mice are able to heal spontaneously cutaneous lesions induced by Leishmania major. In this report, we show that syngeneic gld and lpr mice, lacking a functional Fas system, fail to heal their lesions. This inability to control infection could not be attributed ei