Fas and FasL in the homeostatic regulation of immune responses
β Scribed by David H. Lynch; Fred Ramsdell; Mark R. Alderson
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 998 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The role of Fas in the homeostatic regulation of CD8^+^ T cells after antigen challenge was analyzed in the murine model of lymphocytic choriomeningitis virus (LCMV) infection. Mice homozygous for the lpr mutation and carrying T cell receptor (TCR) Ξ±Ξ² transgenes specific for the LCMV gl
## Abstract Apoptosis is an important mechanism enabling the selection of the nonβselfβreactive T cell repertoire and for maintaining homeostasis in the immune system after it has expanded to combat infections. Highly activated, proliferating T cells become susceptible to apoptosis driven by a numb
Various models have been proposed for the regulation of the primary immune response. Most of the models focus on the ability of the immune system to control a multiplying pathogen, and take into account the cross-regulations between different immune components. In the present study, we integrate the