Fas and fas ligand expression in esophageal squamous cell carcinoma
โ Scribed by rigberg, D.A.; Centeno, J.; Kim, F.S.; Cole, M.A.; Swenson, K.; Maggard, M.; McFadden, D.W.
- Book ID
- 123211329
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 148 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0016-5085
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Background and Objectives: Fas (APO-1) induces apoptosis after binding Fas ligand (FasL). Evidence suggests that tumors may use this interaction to evade the host immune response. Fas/FasL expression has not been reported in esophageal cancer. We hypothesized that Fas expression would render esophag
## BACKGROUND. Although esophageal adenocarcinomas (EADCA) have been shown to have substantially reduced or absent Fas expression, the status of Fas ligand (FasL) in these tumors, especially adenocarcinomas, is largely unknown. ## METHODS. Using immunohistochemistry, the authors investigated FasL