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Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt

✍ Scribed by Stephan Wueest; Reto A. Rapold; Eugen J. Schoenle; Daniel Konrad

Book ID: 113622197
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 373 KB
Volume: 584
Category: Article
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2010.08.052

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## Abstract The purpose of this study was to test a hypothesis that T3 promotes glucose uptake via enhancing insulin‐induced Akt phosphorylation and VAMP2 translocation in 3T3‐L1 adipocytes. T3 significantly enhanced insulin‐induced phosphorylation of Akt, cytoplasma to cell membrane translocations