A phase 1-2 study of a farnesyltransfera
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Elias Jabbour; Hagop Kantarjian; Farhad Ravandi; Guillermo Garcia-Manero; Zeev E
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Article
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2010
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John Wiley and Sons
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English
β 221 KB
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## Abstract ## BACKGROUND: The authors conducted a phase 1/2 study of tipifarnib in combination with idarubicin and cytarabine (IA) in 95 patients with previously untreated acute myeloid leukemia (AML) or highβrisk myelodysplastic syndrome. ## METHODS: Induction consisted of idarubicin 12 mg/m^2