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Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells

✍ Scribed by I. M. K. Vastiau; E. A. Anthonio; M. Brams; C. Brees; S. G. Young; S. Van de Velde; R. J. A. Wanders; G. P. Mannaerts; M. Baes; P. P. Van Veldhoven; M. Fransen

Book ID: 105758360
Publisher: Springer
Year: 2006
Tongue: English
Weight: 568 KB
Volume: 63
Category: Article
ISSN: 1420-682X
DOI: 10.1007/s00018-006-6110-y

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## Abstract Rat aortic lysyl oxidase cDNA was expressed under a metallothionein promoter in Chinese hamster ovary cells using a dihydrofolate reductase selection marker. One methotrexate‐resistant cell line, LOD‐06, generated by transfecting with full‐length cDNA, yielded lysyl oxidase proteins con