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Far-ultraviolet laser ablation of atherosclerotic lesions

✍ Scribed by Ralph Linsker; R. Srinivasan; James J. Wynne; Daniel R. Alonso

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 354 KB
Volume: 4
Category: Article
ISSN: 0196-8092
DOI: 10.1002/lsm.1900040212

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✦ Synopsis

Far-ultraviolet (far-UV) (193 nm) laser radiation ablates arterial wall tissue, including noncalcified atherosclerotic lesions, with no apparent thermal damage to remaining tissue. This effect contrasts sharply with the thermal damage produced by visible-wavelength laser irradiation. The mechanism by which far-UV radiation interacts with tissue is predominantly photochemical rather than photothermal. Potential clinical applications include those in which geometrically precise removal of tissue, without thermal damage to the remaining substrate, is desired. Ultraviolet laser catheterization appears practical with respect to the availability of fiberoptic materials and high-pulse-rate excimer lasers.

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