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Fanconi syndrome after ifosfamide

✍ Scribed by Martin Moncrieff; Anabell Foot

Book ID
104697015
Publisher
Springer
Year
1989
Tongue
English
Weight
141 KB
Volume
23
Category
Article
ISSN
0344-5704

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## Abstract About 10% of children develop Fanconi syndrome (FS) a few months after ifosfamide (IFO) treatment. To establish an animal model, IFO was injected as 4 or 5 treatment courses (TCs, once daily for 3 consecutive days), to adult female rats (AF, 8 mg 100 g^βˆ’1^ body wt, 4 TCs), to young fema

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## Abstract Three children who presented with a Fanconi syndrome induced by the chemotherapeutic drug ifosfamide were found to have renal abnormalities on sonogram examinations. Renal echographic changes consisted in hyperechogenicity of the parenchyma with good corticomedullar differentiation. Aft