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Fanconi anaemia – response to Manoharan

✍ Scribed by Helmut Hanenberg; Kirsten Huck; Sonja Gudowius; Ulrich Göbel; Guido Kobbe; Rainer Haas; Reinhard Kalb; Kornelia Neveling; Detlev Schindler

Book ID
108673925
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
437 KB
Volume
135
Category
Article
ISSN
0007-1048

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Chromosomal breakage frequencies were determined in Fanconi anaemia (FA) blood cultures treated with various concentrations of the polyfunctional alkylating agents mitomycin C, diepoxybutane, and cis-platinum(II)-diammine-dichloride, for which FA cells have a characteristic hypersensitivity. At conc