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Family-based genetic association study of DLGAP3 in Tourette Syndrome

✍ Scribed by Jacquelyn Crane; Jesen Fagerness; Lisa Osiecki; Boyd Gunnell; S. Evelyn Stewart; David L. Pauls; Jeremiah M. Scharf; the Tourette Syndrome International Consortium for Genetics (TSAICG)

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
378 KB
Volume
156
Category
Article
ISSN
1552-4841

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## Abstract The TPH1 and TPH2 genes encode the rate‐limiting enzymes that control serotonin biosynthesis, and serotonin is clearly altered in autism. In the current study, eight SNPs in the TPH1 gene region and eight SNPs within the TPH2 gene were examined by family‐based association tests in a lar