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Family-based association study of ITGB3 in autism spectrum disorder and its endophenotypes

✍ Scribed by Napolioni, Valerio; Lombardi, Federica; Sacco, Roberto; Curatolo, Paolo; Manzi, Barbara; Alessandrelli, Riccardo; Militerni, Roberto; Bravaccio, Carmela; Lenti, Carlo; Saccani, Monica

Book ID
109849285
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
341 KB
Volume
19
Category
Article
ISSN
1018-4813

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## Abstract The TPH1 and TPH2 genes encode the rate‐limiting enzymes that control serotonin biosynthesis, and serotonin is clearly altered in autism. In the current study, eight SNPs in the TPH1 gene region and eight SNPs within the TPH2 gene were examined by family‐based association tests in a lar