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Family and population studies of HLA and coeliac disease in the West of Ireland

✍ Scribed by RACHEL MCKENNA; F. M STEVENS; B MCNICHOLL; S SCHOLZ; E ALBERT; C. F MCCARTHY

Book ID
115093508
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
384 KB
Volume
22
Category
Article
ISSN
0001-2815

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Evidence for a dominant gene mechanism u
Evidence for a dominant gene mechanism underlying coeliac disease in the West of Ireland
✍ Dr. Jaime L. HernΓ‘ndez; Joseph P. Michalski; Candace C. McCombs; Ciaran F. McCar πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 900 KB

Although coeliac disease (CD) is strongly associated with the HLA alleles B8 and DR3, the genetic basis of this illness remains obscure. Recent studies show that at least two unlinked loci are involved. Most studies agree on recessivity at the HLAunlinked locus but differ with respect to dominance o