✦ LIBER ✦

Familial tremulous and myoclonic dystonia with white matter changes in brain magnetic resonance imaging

✍ Scribed by Dr. S. Bohlega; B. Stigsby; M. Z. Al-Kawi; D. R. McLean; P. Ozand; S. Omer; P. Coates

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 496 KB
Volume: 10
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870100420

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We report two families with a disorder, probably autosomal recessive, characterized by tremor of juvenile onset, dystonia, and myoclonus with preserved cognitive, cerebellar, and peripheral nervous system functions. During 4 years' follow‐up, mild spasticity appeared. Magnetic resonance imaging (MRI) revealed mild diffuse changes in the white matter. Central conduction times for visual, motor, and sensory systems were all prolonged. Extensive metabolic work‐up failed to reveal lysosomal, peroxisomal, mitochondrial, or other metabolic abnormalities.

📜 SIMILAR VOLUMES

White matter changes in late onset depre

White matter changes in late onset depression: A magnetic resonance imaging study

✍ R. J. Howard; B. Beats; H. Forstl; P. Graves; J. Bingham; R. Levy 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB 👁 1 views

Functional magnetic resonance imaging re

Functional magnetic resonance imaging reflects changes in brain functioning with sedation

✍ Victoria N Starbuck; Gary G Kay; R. Craig Platenberg; Chin-shoou Lin; Brandon A 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 174 KB 👁 1 views

Functional magnetic resonance imaging (fMRI) studies have demonstrated localized brain activation during cognitive tasks. Brain activation increases with task complexity and decreases with familiarity. This study investigates how sleepiness alters the relationship between brain activation and task f

Absence of white matter changes on magne

Absence of white matter changes on magnetic resonance imaging in children treated with CNS prophylaxis therapy for leukemia

✍ Joel H. Kramer; David Norman; Michael Brant-Zawadzki; Arthur Ablin; Ida M. Moore 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 329 KB 👁 3 views

Cerebral and cerebellar white matter abn

Cerebral and cerebellar white matter abnormalities with magnetic resonance imaging in a child with Feingold syndrome

✍ Vance T. Lehman; Marc C. Patterson; Dusica Babovic-Vuksanovic; Charlotte Rydberg 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 2 views

## Abstract Feingold syndrome is a rare autosomal dominant condition that is characterized by variable expressivity of microcephaly, limb malformations, esophageal atresia, and a host of other malformations. This syndrome results from mutations in the __MYCN__ proto‐oncogene. Few examples of cross‐

White matter lesions on magnetic resonan

White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders

✍ R. Lazarus; R. Prettyman; G. Cherryman 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 76 KB 👁 1 views

## Abstract ## Background The association between white matter lesions on magnetic resonance imaging (MRI) and the presence of vascular risk factors has been investigated in different populations, and results have varied widely. However, this relationship has not been adequately addressed in memor

Quantitation of brain tissue changes ass

Quantitation of brain tissue changes associated with white matter hyperintensities by diffusion-weighted and magnetization transfer imaging: The LADIS (leukoaraiosis and disability in the elderly) study

✍ Stefan Ropele; Alexandra Seewann; Alida A. Gouw; Wiesje M. van der Flier; Reinho 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 453 KB 👁 1 views

## Abstract ## Purpose To explore the value of diffusion‐weighted imaging (DWI) and magnetization transfer imaging (MTI) for the improved detection and quantification of cerebral tissue changes associated with ageing and white matter hyperintensities (WMH). ## Materials and Methods DWI (n = 340)