A boy with both Down's and Sturge-Weber's syndrome was found to have a partial trisomy 21 as a consequence of a familial translocation t(3p-;21q+) which is not reciprocal. Judging from the structure of the involved chromosomes studied by banding and photometrical techniques, the loss of relatively l
✦ LIBER ✦
Familial translocation t(1p-;21q+) associated with Down's syndrome
✍ Scribed by Elzbieta Kubień; Alicja Kleczkowska
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 411 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
Familial occurrence of 1/21 translocation in connection with trisomy 21 was described. The possibilities of inheritance of further chromosome rearrangements arising during the gametogenesis of persons with this translocation were considered.
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