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Familial t(4;21)(q2.4;q2.2) leading to an unbalanced offspring with the down syndrome

โœ Scribed by Park, Jonathan P. ;Graham, John M. ;Wurster-Hill, Doris H. ;Opitz, John M.


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
274 KB
Volume
25
Category
Article
ISSN
0148-7299

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In 1990, Lambotte syndrome was reported as an apparently autosomal recessive multiple congenital anomaly/mental retardation (MCA/MR) syndrome observed in 4 of 12 sibs from a probably consanguineous mating [Verloes et al., Am J Med Genet 1990; 37:119-123]. Major manifestations included intrauterine g