Familial small supernumerary marker chromosome (sSMC) (14)(:P11–q11:)In a child with translocation down syndrome
✍ Scribed by Babu Rao Vundinti; Seema Korgaonkar; Kanjaksha Ghosh
- Book ID
- 107598620
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 782 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0019-5456
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## Abstract In the neurodevelopmentally impaired population the frequency of small supernumerary marker chromosomes (sSMC) is about 0.3%. To find the origin of a sSMC in a 4‐year‐old boy with Asperger syndrome (AS) a microarray‐based comparative genomic hybridization (aCGH), using a 135K‐feature wh
## Abstract Unstable, gene‐rich pericentric regions have been associated with various structural aberrations including small supernumerary marker chromosomes (sSMCs). We hereby report on a complex pure mosaic sSMCs derived from chromosomes 11 and 19 in a child featuring multiple congenital anomalie