Familial pericentric inversion of chromosome 12
โ Scribed by I. Voiculescu; G. Barbi; G. Wolff; P. Steinbach; Elke Back; W. Schempp
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 367 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0340-6717
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๐ SIMILAR VOLUMES
Two cases of pericentric inversion of chromosome 12 are presented, one 46,XX,inv(12)(p13;q11) and the other was also a heterozygotic carrier of the inversion. These inversions were detected among 4035 cytogenetic analyses carried out in patients with psychosomatic retardation and/or malformations (3
A pericentric inversion of chromosome 12 has been followed in three large independently ascertained Danish families. Out of a total number of 52 persons examined, 25 were found to carry the inversion. The breakpoints in all three families were localized to p13 and q13, resulting in more than one-thi