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Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta–cardiac myosin heavy chain mutation

✍ Scribed by E.James Gruver; Diane Fatkin; G.Alfred Dodds; Joseph Kisslo; Barry J Maron; J.G Seidman; Christine E Seidman


Book ID
113980653
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
140 KB
Volume
83
Category
Article
ISSN
0002-9149

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✍ Roberta Roncarati; Michael V.G. Latronico; Beatrice Musumeci; Stefania Aurino; A 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease. Fourteen sarcomeric and sarcomere-related genes have been implicated in HCM etiology, those encoding β-myosin heavy chain (__MYH7__) and cardiac myosin binding protein C (__MYBPC3__) reported as the most frequently mutated