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Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation

✍ Scribed by Boukje De Vries; Anine H. Stam; Martin Kirkpatrick; Kaate R.J. Vanmolkot; Jan B. Koenderink; Jeroen J.M.W. Van Den Heuvel; Bas Stunnenberg; David Goudie; Jay Shetty; Vivek Jain; Judith Van Vark; Gisela M. Terwindt; Rune R. Frants; Joost Haan; Arn M.J.M. Van Den Maagdenberg; Michel D. Ferrari


Book ID
109111325
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
96 KB
Volume
50
Category
Article
ISSN
0013-9580

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Familial hemiplegic migraine (FHM) is an autosomal dominant form of migraine with aura. The disease is caused by mutations of at least three genes among which two have been identified, CACNA1A and ATP1A2. Very few mutations have been identified so far in ATP1A2. We screened the coding sequence of AT