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Familial expression of anti-Saccharomyces cerevisiae mannan antibodies in Crohn’s disease and ulcerative colitis: a GISC study

✍ Scribed by V Annese; A Andreoli; A Andriulli; R D’Inca’; P Gionchetti; A Latiano; G Lombardi; A Piepoli; D Poulain; B Sendid; J.F Colombel

Book ID: 119390723
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 576 KB
Volume: 96
Category: Article
ISSN: 0002-9270
DOI: 10.1016/s0002-9270(01)02606-5

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Background: Antibodies against mannan, a component of the yeast Saccharomyces cerevisiae cell wall, are more frequently found in Crohn's disease (CD) patients with low levels of mannan-binding lectin (MBL). MBL concentration depends on genetic polymorphisms. The aim of this study was to evaluate whe