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Familial cryptic (20;21) translocation identified by in situ hybridization technologies

✍ Scribed by Leppig, Kathleen A. ;Ball, Susie ;Au, Kam ;Opheim, Kent E. ;Norwood, Thomas


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
239 KB
Volume
93
Category
Article
ISSN
0148-7299

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## Abstract In childhood B‐lineage acute lymphoblastic leukemia (ALL), the most common genetic change, the __ETV6‐CBFA2__ (__TEL‐AML1__) fusion resulting from the cryptic t(12;21)(p13;q22) is associated with a favorable outcome. Therefore, it is important to identify patients with this translocatio