Familial balanced (7;11;21)translocation and Down's syndrome in two siblings
โ Scribed by E. Schwinger; Margareta Mikkelen; Mathilda Niesen
- Book ID
- 119838224
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 268 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0009-9163
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A boy with both Down's and Sturge-Weber's syndrome was found to have a partial trisomy 21 as a consequence of a familial translocation t(3p-;21q+) which is not reciprocal. Judging from the structure of the involved chromosomes studied by banding and photometrical techniques, the loss of relatively l
Translocation t(11;21)(q24;q11.2) is a rare but recurrent chromosomal abnormality associated with myelodysplastic syndrome (MDS) that until now has not been characterized at the molecular level. We report here results of a molecular cytogenetic analysis of this translocation in a patient with refrac