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Familial association between type 1 diabetes and other autoimmune and related diseases

✍ Scribed by K. Hemminki; X. Li; J. Sundquist; K. Sundquist


Publisher
Springer
Year
2009
Tongue
English
Weight
162 KB
Volume
52
Category
Article
ISSN
0012-186X

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Background Type 1 diabetes (T1D) is a clinically heterogeneous disease. The presence of associated autoimmune diseases (AAIDs) may represent a distinct form of autoimmune diabetes, with involvement of specific mechanisms. The aim of this study was to find predictors of AAIDs in the Type 1 Diabetes G

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One hundred and three unrelated patients with Type 1 (insulin-dependent) diabetes were typed for HLA, properdin factor B (BF), glyoxalase 1 (GLO), Kidd blood group, and 24 other genetic markers. Observed distributions of marker phenotypes among these patients were compared with those expected accord