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False localization of acid phosphatase activity in the nuclear envelope and endoplasmic reticulum of peritoneal macrophages

โœ Scribed by Hoefsmit, E. C. M. ;Eestermans, I. L. ;Korn, C. ;Van Duijn, P.


Publisher
Springer
Year
1985
Tongue
English
Weight
993 KB
Volume
17
Category
Article
ISSN
0018-2214

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The pentameric B subunit of verotoxin (VT) mediates the attachment to cell surface globotriaosyl ceramide (Gb3) to facilitate receptor-mediated endocytosis of the toxin. In highly toxin-sensitive tumor cells, the holotoxin and VT1 B subunit is targeted intracellularly to elements of the endoplasmic