Pathogenic or not? And if so, then how?
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Janita Thusberg; Mauno Vihinen
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Article
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2009
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John Wiley and Sons
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English
β 367 KB
Many gene defects are relatively easy to identify experimentally, but obtaining information about the effects of sequence variations and elucidation of the detailed molecular mechanisms of genetic diseases will be among the next major efforts in mutation research. Amino acid substitutions may have d