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FAK inhibition decreases cell invasion, migration and metastasis in MYCN amplified neuroblastoma

✍ Scribed by Megison, Michael L.; Stewart, Jerry E.; Nabers, Hugh C.; Gillory, Lauren A.; Beierle, Elizabeth A.

Book ID
121635216
Publisher
Springer
Year
2012
Tongue
English
Weight
848 KB
Volume
30
Category
Article
ISSN
0262-0898

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## Abstract Coexpression for c‐Kit receptor and its ligand stem cell factor (SCF) has been described in neuroblastoma (NB) cell lines and tumors, suggesting the existence of an autocrine loop modulating tumor growth. We evaluated c‐Kit and SCF expression by immunohistochemistry in a series of 75 pr