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FAK-dependent ERK regulation of caco-2 intestinal epithelial biology during motility requires PI 3-kinase and Src

โœ Scribed by Matthew A. Sanders; Marc D. Basson


Book ID
119429540
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
194 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract Herein, we investigated the survival roles of Fak, Src, MEK/Erk, and PI3โ€K/Aktโ€1 in intestinal epithelial cancer cells (HCT116, HT29, and T84), in comparison to undifferentiated and differentiated intestinal epithelial cells (IECs). We report that: (1) cancer cells display striking anoi