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Failure to Enhance the in Vivo Killing of Human Ovarian Carcinoma by Sequential Treatment with Dequalinium Chloride and Tumor Necrosis Factor

โœ Scribed by Alberto Manetta; Dennis Emma; Gisela Gamboa; Shu Liao; Michael Berman; Philip Disaia


Book ID
115615877
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
329 KB
Volume
50
Category
Article
ISSN
0090-8258

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## BACKGROUND. Previous studies have demonstrated that treatment of human tumor cell lines with a combination of cis-diamminedichloroplatinum (CDDP) and tumor necrosis factor-a (TNF-a) results in additivelsynergistic cytotoxic effects and reverses tumor cell resistance to TNF drugs. Free radical i